发明名称 RADIOPHARMACEUTICAL FOR DIAGNOSTIC IMAGING CONTAINING A TECHNETIUM-99M NITRIDE HETEROCOMPLEX
摘要 A radiopharmaceutical for diagnostic imaging containing as an active ingredient a technetium-99m nitride heterocomplex comprising technetium-99m nitride and two different ligands coordinated therewith, i.e., a bisphosphinoamine compound as a .pi. electron acceptor and a bidentate ligan d as a .pi. electron donor and represented by the following formula (1): [99mTc(N)(PNP)(XY)]+ (1)wherein 99mTc(N) is technetium-99m nitride, PNP is a bisphosphinoamine compound and XY is a bidentate ligand, is markedly accumulated in heart and adrenal glands and hence is useful for radiodiagnostic imaging of heart and adrenal glands.
申请公布号 CA2417392(C) 申请公布日期 2007.09.11
申请号 CA20012417392 申请日期 2001.07.25
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 BOSCHI, ALESSANDRA;REFOSCO, FIORENZO;DUATTI, ADRIANO;BOLZATI, CRISTINA;TISATO, FRANCESCO;UCCELLI, LICIA
分类号 A61K51/00;A61K51/04;A61K51/02 主分类号 A61K51/00
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