| 摘要 |
An insulin like growth factor-1(IGF-I) mimicking peptide is provided to perform functions or actions identical to natural-occurring IGF-I and realize much better stability and skin permeation than natural-occurring IGF-I. A composition comprising the peptide is provided to be able to show excellent efficacy on the treatment, prevention and improvement of diseases or conditions demanding IGF-I activities, thereby being advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics. A peptide having the activity of IGF-I and derived from the IGF-I comprises an amino acid sequence selected from SEQ ID : N0s. 2 to 8. The composition for improving skin conditions or treating a periodontal disease comprises a pharmaceutically effective amount of the peptide as an effective ingredient and a cosmetically acceptable carrier or a pharmaceutically acceptable carrier. To improve a skin condition or treat a periodontal disease, the composition comprising the peptide is administered to a subject.
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