PROPHYLACTIC OR THERAPEUTIC AGENT FOR ALLERGIC OPHTHALMIC DISEASE OR ALLERGIC NASAL DISEASE COMPRISING TRICYCLIC TRIAZOLOBENZOAZEPINE DERIVATIVE

摘要

Disclosed is a pharmaceutical composition for prevention or treatment of an allergic ophthalmic disease or an allergic nasal disease, which comprises 7,8-dimethoxy-4(5H),10-dioxo-1H- 1,2,3-triazolo[4,5-c][1]benzoazepine or 2-(1- isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy- 4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzoazepine, or a pharmacologically acceptable salt thereof. The pharmaceutical composition produces little adverse side effects and has a potent prophylactic effect and a potent therapeutic effect in a late phase where the treatment-resistance against an already available eye drop may be induced. The composition can be suitably used for topical administration.