| 发明名称 |
DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF ß-SECRETASE |
| 摘要 |
<p>The present invention provides a 10,11-dihydrospiro[dibenzo[a,d][7]annulene-5,4'-imidazol]-5'(1'H)-one compound of formula (I). Also provided are methods and compositions for the inhibition of ß-secretase (BACE) and the treatment of ß-amyloid deposits and neurofibrillary tangles.</p> |
| 申请公布号 |
WO2007100536(A1) |
申请公布日期 |
2007.09.07 |
| 申请号 |
WO2007US04309 |
申请日期 |
2007.02.16 |
| 申请人 |
WYETH;QUAGLIATO, DOMINICK ANTHONY;ANDRAE, PATRICK MICHAEL;FAN, YI |
发明人 |
QUAGLIATO, DOMINICK ANTHONY;ANDRAE, PATRICK MICHAEL;FAN, YI |
| 分类号 |
C07D235/02;A61K31/4184;A61P25/28 |
主分类号 |
C07D235/02 |
| 代理机构 |
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