| 摘要 |
Magnesium organic synthesis agent (A) comprises a solvent with at least an oxygen donor compound (I); and at least a magnesium organic compound (II) excluding benzyl compound (III) and propen-3-yl compound (IV). Magnesium organic synthesis agent (A) comprises a solvent with at least an oxygen donor compound of formula (I); and at least a magnesium organic compound (II) of formula (R-MgX) or (R-Mg-R) excluding benzyl-MgX compound of formula (III) and propen-3-yl-MgX compound (IV) of formula (R 3>2C=C(R 3>)-CR 3>2-MgX). R 1>, R 2>H, optionally functionalized 1-20C-(cyclo)alkyl- or -(cyclo)alkyloxy, 1-12C-(het)aryl or -aryloxy; R : optionally functionalized 1-20C-(halo)alkyl, -alkoxy-, 2-20C-haloalkoxy, 2-20C-alkenyl, 2-20C-alkynyl, 3-8C-cycloalkyl and/or optionally functionalized 3-12C- phenyl, -phenoxy, -(het)aryl, where the halo is F or Cl; X : F, Cl, Br, I, triflate and/or tosylate; and R 3>H, F, Cl, 1-8C-(halo)alkyl, 1-8C(halo)-alkoxy, 2-6C-alkenyl, 5-6C-cyclolkyl, trimethylsilyl, phenyl and/or phenoxy. Provided that: when R 1>is H, then R 2>is not H. An independent claim is included for a method for the preparation of (A) comprising preparing and dispersing magnesium in a solvent, activating the magnesium and adding a compound (V) of formula (R-X). [Image]. |
