Accuracy improvement in strong ion difference for blood gas testing

摘要

An improved bicarbonate determination with variability of apparent dissociation constant in Henderson-Hasselbach equation or Henderson equation with Henry's law is described. The improved bicarbonate is utilized in the determination of improved Strong Ion Difference (SID) and Strong Ion Difference Excess (SIDE) as the change in SID from the reference value at pH=7.4, pCO2=5.33 Kpa (or 40 torr) for blood gas testing.