Amine-Based Compound and Use Thereof

摘要

Novel amine compounds which are represented by the following formula (1) and efficacious against diseases such as a viral infectious disease with HIV, rheumatism, and cancer metastasis; typically, A₁ and A₂ represent a hydrogen atom or a substitutable monocyclic or polycyclic heteroaromatic ring and W represents a substitutable benzene ring or any group represented by the following formula (10) or (11): where X represents O, CH₂, C(-O), NR₁₁, or CHR₃₅ and D represents a group represented by the following formula (6): where Q represents a single bond, NR₁₂, or a group represented by the formula (13): and Y represents a group represented by the following formula (7): where z represents a substitutable monocyclic or polycyclic aromatic ring; and B represents -NR₂₅R₂₆; and R₁ to R₂₆ in the above formulae represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group.