| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an artificial bone with sustained-release property of chemical and a manufacturing method thereof, sustain releasing an antibacterial medicine effectively working on anaerobiic bacteria over a long period of time as much as about eight weeks, curing myelitis with a small quantity of antibacterial medicine applied, making calcium phosphate porous material act as a foothold for osteoplasty, and metabolizing all of antibacterial medicine, calcium phosphate porous material and an antibacterial medicine carrier. <P>SOLUTION: This artificial bone with sustained-release property of chemical and a manufacturing method thereof are characterized in that one or two or more kinds of antibacterial medicines selected from norfloxacin, ofloxacin, levofloxacin, sparfloxacin, and gatifloxacin, and one or two or more kinds of bioabsorptive polymers not derived from a living body and selected from polycaprolactone, polyethylene glycol, lactic acid-glycolic acid copolymer, and caprolactone-DL lactic acid copolymer are made to exist in pores of artificial bone which has a porosity of 50% to 80% and is made of porous tricalcium phosphate not derived from a living body. <P>COPYRIGHT: (C)2007,JPO&INPIT |
