发明名称 ARYLALKANOIC ACID DERIVATIVE
摘要 A compound represented by the formula (I): wherein Ar is an optionally substituted aromatic ring; Xa, Xc, Ya, Yc, Z 1 and Z 2 are each a bond, O, S, -CO-, -CS-, - CR 3 (OR 4 ) -, -NR 5 -, -SO-, -SO 2 -, -CONR 6 - or -NR 6 CO- (wherein R 3 , R 4 , R 5 and R 6 are as defined in the specification); Xb and Yb are each a bond or a divalent hydrocarbon group having 1 to 20 carbon atoms; R 1 is an optionally substituted hydrocarbon group; ring A is an optionally further substituted aromatic ring, provided that the ring should not be benzimidazole; n is an integer of 1 to 8; ring B is an optionally further substituted aromatic ring, provided that the ring should not be oxazole; W is a divalent saturated hydrocarbon group having 1 to 20 carbon atoms; and R 2 is -OR 8 or -NR 9 R 10 (wherein R 8 , R 9 and R 10 are as defined in the specification) or a salt thereof, is useful as an agent for the prophylaxis or treatment of diabetes and the like.
申请公布号 EP1829863(A1) 申请公布日期 2007.09.05
申请号 EP20050811684 申请日期 2005.11.25
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 MAEKAWA, TSUYOSHI;UJIKAWA, OSAMU;ABE, HIDENORI;NOMURA, IZUMI
分类号 A61K31/426;C07D213/30;A61K31/415;A61K31/422;A61K31/427;A61K31/44;A61K31/4402;A61K31/4709;A61K31/506;A61P3/02;A61P3/06;A61P3/10;A61P43/00;C07D213/50;C07D213/64;C07D213/69;C07D231/20;C07D231/22;C07D277/20;C07D277/56;C07D401/06 主分类号 A61K31/426
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