发明名称 |
METHOD OF PREPARING ANTIBODY BY USE OF CELL HAVING ITS FUCOSE TRANSPORTER FUNCTION INHIBITED |
摘要 |
The present invention relates to a method of producing a recombinant protein particularly an antibody using a cell in which the function of a fucose transporter is inhibited. According to the present invention, a cell in which the expression of fucose transporter genes on both homologous chromosomes is artificially suppressed is provided.
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申请公布号 |
EP1829962(A1) |
申请公布日期 |
2007.09.05 |
申请号 |
EP20050800043 |
申请日期 |
2005.10.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
TSUCHIYA, MASAYUKI;IIJIMA, SHIGEYUKI;SUGO, IZUMI;SEKIMORI, YASUO;HABU, KIYOSHI;SUGIMOTO, MASAMICHI |
分类号 |
A61K39/395;C12N15/00;A01H5/00;A01K67/027;A61P9/00;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/00;A61P37/08;C07K14/47;C12N5/00;C12P21/02;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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