Substituted pyrazoles of general formula methods of manufacturing them, compositions containing them, and methods of using them to, for example, treat autoimmune diseases mediated by cathepsin S, and inhibit cathepsin S activity, are described.
申请公布号
US7265102(B2)
申请公布日期
2007.09.04
申请号
US20050147923
申请日期
2005.06.08
申请人
ORTHO MCNEIL PHARMACEUTICAL, INC.
发明人
CAI HUI;EDWARDS JAMES P.;MEDUNA STEVEN P;PIO BARBARA A.;WEI JIANMEI