| 摘要 |
A method for inducing peritonitis in Mongolian gerbils is provided to improve reproducibility of peritonitis induction, identify pathophysiologic mechanism of peritonitis in human by using Mongolian gerbils showing similar pathophysiology to human, and prevent and treat peritonitis of human. Peritonitis is induced in Mongolian gerbils by orally administering 25-35 mg/kg, preferably 30 mg/kg of a nonsteroidal anti-inflammatory drug(NSAID) into 4-6 week-, preferably 5 week-old Mongolian gerbils, wherein the nonsteroidal anti-inflammatory drug is aspirin, indometacin, ibuprofen, ketoprofen or tolmetin, preferably indometacin.
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