发明名称 |
Process of making di-aryl urea compounds |
摘要 |
Disclosed is a process of making compounds of formula(I): wherein R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4 </SUB>and Ra of formula(I) are defined herein. The product compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation. Also disclosed are intermediates useful in making such compounds.
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申请公布号 |
US7265222(B2) |
申请公布日期 |
2007.09.04 |
申请号 |
US20040881589 |
申请日期 |
2004.06.30 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
HADDAD NIZAR;WEI XUDONG;SENANAYAKE CHRIS HUGH;XU JINGHUA;YEE NATHAN |
分类号 |
C07D239/34;C07C275/34;C07D239/46;C07D239/54;C07D239/545 |
主分类号 |
C07D239/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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