| 发明名称 |
АНТИТЕЛО ПРОТИВ ГЛИПИКАНА 3 |
| 摘要 |
An antibody capable of binding to a specific region of glypican 3, as well as a humanized antibody created based on that antibody are disclosed. The anti-GPC3 antibody of the invention has a higher ADCC activity and CDC activity compared with those of a conventional antibody. The antibody of the present invention is useful as a cell growth inhibitor, an anticancer agent and an agent for diagnosis of cancers. |
| 申请公布号 |
RU2006104842(A) |
申请公布日期 |
2007.08.27 |
| 申请号 |
RU20060104842 |
申请日期 |
2005.07.08 |
| 申请人 |
ЧУГАИ СЕЙЯКУ КАБУСИКИ КАЙСЯ (JP) |
发明人 |
НАКАНО Кийотака (JP);ЙОСИНО Такеси (JP);НЕЗУ Дзун-ити (JP);ЦУНОДА Хироюки (JP);ИГАВА Томоюки (JP);КОНИСИ Хироко (JP);ТАНАКА Мегуми (JP);ЗУГО Изуми (JP);КАВАИ Сигето (JP);ИСИГУРО Такахиро (JP);КИНОСИТА Ясуко (JP) |
| 分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
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