发明名称 4-[(2,4-DICHLORO-5-METHOXYPHENYL)AMINO]-6-ALKOXY-7-ETHYNYL-3-QUINOLINECARBONITRILES FOR THE TREATMENT OF ISCHEMIC INJURY
摘要 This invention relates to compounds of the formula (I): wherein: R is methyl or ethyl; R' and R" are independently alkyl of 1 to 3 carbon atoms, or R' and R", taken together with the nitrogen to which they are attached, can form a 5 or 6 membered saturated ring which may optionally contain an additional heteroatom selected from NR"', O or S(O)n; n is 0-2; and R"' is hydrogen or alkyl of 1 to 3 carbon atoms; and pharmaceutically acceptable salts thereof, and their use for inhibiting vascular permeability caused by disease, injury or other trauma.
申请公布号 KR20070085413(A) 申请公布日期 2007.08.27
申请号 KR20077011472 申请日期 2007.05.21
申请人 WYETH 发明人 BOSCHELLI DIANE HARRIS;ZALESKA MARGARET;BARRIOS SOSA ANA CAROLINA
分类号 C07D215/44;A61K31/4706;C07D215/54 主分类号 C07D215/44
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