| 摘要 |
<p>Compounds of the formula (I), or pharmaceutically acceptable salts thereof, wherein R2 is (CR3R4) n-NR5R6 and m, p, q, Ar, R1, R 3, R4, R5 and R6 are as defined in the claims, which are selective antagonists of 5-HT6 and/or 5-HT2A. Also provided are compositions comprising these compounds and their use in the preparation of medicaments for treating central nervous system disease states selected from psychoses, schizophrenia, manic depressions, neurological disorders, memory disorders, attention deficit disorder, Parkinson's disease, amyotrophic lateral scierosis, Alzheimer's disease, food uptake disorders and Huntington's disease.</p> |
