SYNERGETIC FILLING AGENT COMPOSITION

摘要

FIELD: pharmacy. ^ SUBSTANCE: invention proposes a pharmaceutical agent comprising a hardly pressed substance, and a filing agent composition consisting of 5-30 wt.-% of copolymer of polyvinylpyrrolidone with vinyl acetate and siliconized microcrystalline cellulose. The used copolymer consists of 60-80 wt.-% of polyvinylpyrrolidone and 20-40 wt.-% of vinyl acetate. Invention provides preparing a pharmaceutical tablet showing the strength index at least 3 kPa at pressing effort 2000-500 pounds being without increasing a tablet size. Prepared hardness is sufficient in order to prevent damage of tablet in its further processing including applying a cover and package. ^ EFFECT: improved properties of filling agent. ^ 2 cl, 7 dwg