Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.
申请公布号
US2007196374(A1)
申请公布日期
2007.08.23
申请号
US20060560524
申请日期
2006.11.16
申请人
BACA MANUEL;WELLS JAMES A;PRESTA LEONARD G;LOWMAN HENRY B;CHEN YVONNE M
发明人
BACA MANUEL;WELLS JAMES A.;PRESTA LEONARD G.;LOWMAN HENRY B.;CHEN YVONNE M.
