发明名称 |
METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOL |
摘要 |
<p num="1">A method of stereoselectively producing an optically active alcohol characterized by comprising reducing an aromatic ketone by using an optically active 2-[bis(4-methoxyphenyl)hydroxymethyl]pyrrolidine, sodium borohydride and chlorotrimethylsilane. According to this method, an optically active alcohol showing a high enantioselectivity can be produced even on a large scale.
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申请公布号 |
CA2642388(A1) |
申请公布日期 |
2007.08.23 |
申请号 |
CA20072642388 |
申请日期 |
2007.02.13 |
申请人 |
KOTOBUKI PHARMACEUTICAL CO., LTD. |
发明人 |
TOMIYAMA, HIROSHI;YOKOTA, MASAYUKI |
分类号 |
C07C29/143;C07B53/00;C07B61/00;C07C33/22;C07C67/31;C07C69/65;C07D205/08;C07D263/14 |
主分类号 |
C07C29/143 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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