发明名称 METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOL
摘要 <p num="1">A method of stereoselectively producing an optically active alcohol characterized by comprising reducing an aromatic ketone by using an optically active 2-[bis(4-methoxyphenyl)hydroxymethyl]pyrrolidine, sodium borohydride and chlorotrimethylsilane. According to this method, an optically active alcohol showing a high enantioselectivity can be produced even on a large scale.
申请公布号 CA2642388(A1) 申请公布日期 2007.08.23
申请号 CA20072642388 申请日期 2007.02.13
申请人 KOTOBUKI PHARMACEUTICAL CO., LTD. 发明人 TOMIYAMA, HIROSHI;YOKOTA, MASAYUKI
分类号 C07C29/143;C07B53/00;C07B61/00;C07C33/22;C07C67/31;C07C69/65;C07D205/08;C07D263/14 主分类号 C07C29/143
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