发明名称 PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS ACIDOS FENILA- CETICOS SUSTITUIDOS.
摘要 <p>1,192,629. o-Anilino-phenylacetic acids. J. R. GEIGY A.G. 6 Oct., 1967 [7 Oct., 1966], No. 45725/67. Heading C2C. o-Anilino-phenylacetic acids of the general formula wherein R 1 is a C 1-4 alkyl or C 1-4 alkoxy group, a fluorine or chlorine atom or the trifluoromethyl group; R 2 is a hydrogen atom or is defined as R 1 ; R 3 is a hydrogen atom, a C 1-4 alkyl or C 1-4 alkoxy group or a fluorine or chlorine atom; R 4 is defined as R 2 ; and R 5 and R 6 are each a hydrogen atom or a C 1-2 alkyl or benzyl group, and when R 6 is a hydrogen atom R 5 is a C 1-5 alkyl group, are prepared by reaction of a 2-indolinone derivative and a substituted halobenzene of the respective general formulµ wherein Hal is bromine or iodine, in the presence of an acid binding agent and, if necessary, a catalyst. [o - (2,3 - Xylidino) - phenyl] - acetic acid is a novel compound.</p>
申请公布号 ES345830(A1) 申请公布日期 1968.11.16
申请号 ES19300003458 申请日期 1967.10.06
申请人 J. R. GEIGY A. G. 发明人
分类号 A61K31/19;(IPC1-7):A61K/ 主分类号 A61K31/19
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