发明名称 Polynucleotides and polypeptide sequences involved in the process of bone remodeling
摘要 <p>This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling, variants and derivatives of the polynucleotides and corresponding polypeptides, uses of the polynucleotides, polypeptides, variants and derivatives, and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are the isolation and identification of polynucleotides polypeptides variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.</p>
申请公布号 AU2007215334(A1) 申请公布日期 2007.08.23
申请号 AU20070215334 申请日期 2007.02.13
申请人 ALETHIA BIOTHERAPEUTICS INC. 发明人 MARIO FILION;ROY RABINDRANAUTH SOOKNANAN;GILLES BERNARD TREMBLAY
分类号 C12N15/60;A61K31/7088;A61K38/17;A61K38/19;A61K38/22;A61K38/43;A61K38/44;A61K38/46;A61K38/48;A61K38/51;A61K38/53;A61K39/395;A61K48/00;A61P19/08;C07K14/47;C07K14/52;C07K14/575;C07K16/18;C07K16/24;C07K16/26;C07K16/28;C07K16/40;C12N5/10;C12N5/16;C12N9/00;C12N9/02;C12N9/14;C12N9/64;C12N9/88;C12N15/12;C12N15/16;C12N15/19;C12N15/52;C12N15/53;C12N15/55;C12N15/57;C12N15/63;C12P21/08;C12Q1/00;C12Q1/68;C40B40/02;C40B40/08;G01N33/53;G01N33/566 主分类号 C12N15/60
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