发明名称 METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES.
摘要 <p>The present invention relates to a novel chemical process that provides novel vehicle derivatives that are exceptional 1,2- or 1,3-aminothiol specific reagents for conjugation to unprotected targeted compounds (e.g., polypeptides, peptides, or organic compounds) having or modified to have a 1,2- or 1,3 aminothiol group. The invention further relates to the methods of using novel water-soluble polymer derivatives and conjugates thereof.</p>
申请公布号 MX2007008827(A) 申请公布日期 2007.08.22
申请号 MX20070008827 申请日期 2006.01.24
申请人 AMGEN INC. 发明人 BENNY C. ASKEW, JR.;DERIN C. D'AMICO
分类号 A61K47/48 主分类号 A61K47/48
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