发明名称 |
Rage-related methods for treating inflammation |
摘要 |
The present invention provides a method for treating inflammation in a subject which comprises administering to the subject soluble receptor for advanced glycation endproduct (sRAGE) in an amount effective to inhibit binding of advanced glycation endproducts (AGEs) to RAGE thereby treating inflammation in the subject. The present invention also provides for a method for treating inflammation in a subject which comprises administering to the subject an agent in an amount effective to inhibit the interaction between receptor for advanced glycation endproduct (RAGE) and its ligand thereby treating inflammation in the subject.
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申请公布号 |
US7258857(B2) |
申请公布日期 |
2007.08.21 |
申请号 |
US20010872185 |
申请日期 |
2001.06.01 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
STERN DAVID M.;HEROLD KEVAN;YAN SHI DU;SCHMIDT ANN MARIE;LAMSTER IRA |
分类号 |
A61K39/395;A61K31/00;A61K38/17;C07K16/18;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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