Derivatives of 3-phenyl-n-(2-(4-benzyl)-piperidin-1-yl)-ethyl)-acrylamid with ccr-3-receptor antagonistic activity for use in the treatment of inflammations and allergic conditions

摘要

This invention relates to organic compounds of formula I, in which Ar¹ is unsubstituted phenyl substituted by one or more halogen atoms; Ar² is unsubstituted phenyl or phenyl substituted by one or more substituents selected from the group consisting of halogen, cyano and C₁-C₈-alkoxy; R¹ is hydrogen or methyl optionally substituted by hydroxy; R¹⁰ is hydrogen or hydroxy; and pharmaceutically acceptable salts thereof. Compositions containing them, methods for their preparation and their use as pharmaceuticals are also described.