| 发明名称 |
ADAMANTYL DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME. |
| 摘要 |
<p>The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.</p> |
| 申请公布号 |
MX2007008238(A) |
申请公布日期 |
2007.08.17 |
| 申请号 |
MX20070008238 |
申请日期 |
2006.01.05 |
| 申请人 |
ABBOTT LABORATORIES. |
发明人 |
HONG YONG;JAMES T. LINK;JEFFREY J. ROHDE;JYOTI R. PATEL;QI SHUAI;JURGEN DINGES;BRYAN K. SORENSEN;VINCE S. YEH;MARTIN WINN |
| 分类号 |
C07C235/14;A61K31/4402;A61P3/10;C07C317/16;C07C323/41;C07D207/48;C07D213/64;C07D233/54;C07D257/04;C07D261/08 |
主分类号 |
C07C235/14 |
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