| 摘要 |
Provided is an industrially applicable process for producing 1,2-cis-2-fluorocyclopropane-1-carboxylic ester. A process for producing a compound represented by formula (3): [wherein R<SUP>1 </SUP>represents, for example, a C1-C8 alkyl group], which process includes reacting a compound represented by formula (1): [wherein X<SUP>1 </SUP>represents a hydrogen atom, a chlorine atom, a bromine atom, or an iodine atom; X<SUP>2 </SUP>represents a hydrogen atom, a chlorine atom, a bromine atom, or an iodine atom; X<SUP>1 </SUP>and X<SUP>2 </SUP>are not simultaneously hydrogen atoms; and R<SUP>1 </SUP>has the same meaning as defined in formula (3)] with a reducing agent represented by formula (2): <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUP>1</SUP>BH<SUB>m</SUB>R<SUP>2</SUP><SUB>n</SUB> ( 2 - 1 )<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>or<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUP>2</SUP>(BH<SUB>m</SUB>R<SUP>2</SUP>n)<SUB>2</SUB> ( 2 - 2 )<?in-line-formulae description="In-line Formulae" end="tail"?> [wherein M<SUP>1 </SUP>represents an alkali metal atom; M<SUP>2 </SUP>represents an alkaline earth metal atom or a zinc atom; R<SUP>2 </SUP>represents, for example, a hydrogen atom; m represents an integer from 1 to 4; n represents an integer from 0 to 3; and the sum of m and n is 4] in the presence of an aprotic polar solvent, and a Lewis acid such as a halide of an atom selected from among, for example, boron, magnesium, and aluminum.
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