发明名称 |
Synergistic analgesic combination of opioid analgesic and cyclooxygenase-2 inhibitor |
摘要 |
Disclosed is a pharmaceutical composition, comprising two analgesic compounds and/or pharmaceutically acceptable salts thereof consisting of celecoxib and/or at least one pharmaceutically acceptable salt thereof and oxycodone and/or at least one pharmaceutically acceptable salt thereof, said two analgesic compounds in an amount sufficient to provide an analgesic effect in a human patient. Also disclosed is a method of effectively treating pain in humans or other mammals, comprising orally administering to the patient an oral dosage form comprising two analgesic compounds consisting of celecoxib and/or at least one pharmaceutically acceptable salt thereof and oxycodone and/or at least one pharmaceutically acceptable salt thereof, said two analgesic compounds in an amount sufficient to provide an analgesic effect in a human patient.
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申请公布号 |
US2007191412(A1) |
申请公布日期 |
2007.08.16 |
申请号 |
US20070698394 |
申请日期 |
2007.01.26 |
申请人 |
BURCH RONALD M;GOLDENHEIM PAUL D;SACKLER RICHARD S |
发明人 |
BURCH RONALD M.;GOLDENHEIM PAUL D.;SACKLER RICHARD S. |
分类号 |
A61K9/20;A61K31/4353;A61F2/02;A61K9/02;A61K9/08;A61K9/10;A61K9/28;A61K9/48;A61K31/12;A61K31/485;A61K31/54;A61K45/00;A61K45/06;A61P25/00;A61P25/04;A61P29/00 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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