发明名称 |
Cycloalkanopyridine derivative |
摘要 |
Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.
|
申请公布号 |
US2007191419(A1) |
申请公布日期 |
2007.08.16 |
申请号 |
US20050590585 |
申请日期 |
2005.03.04 |
申请人 |
TAKAHASHI HIROBUMI;SUGIMOTO YUICHI;YOSHIZUMI TAKASHI;KATO TETSUYA;ASAI MASANORI;MIYAZOE HIROSHI |
发明人 |
TAKAHASHI HIROBUMI;SUGIMOTO YUICHI;YOSHIZUMI TAKASHI;KATO TETSUYA;ASAI MASANORI;MIYAZOE HIROSHI |
分类号 |
A61K31/435;A61K31/403;A61K31/438;A61K31/4545;A61K31/46;A61K31/4709;A61K31/496;A61K31/55;A61P3/04;A61P9/00;A61P13/00;A61P25/02;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P25/36;A61P43/00;C07D221/04;C07D239/70;C07D401/06;C07D401/14;C07D451/00;C07D451/02;C07D471/04;C07D471/10;C07D487/10;C07D491/10;C07D491/20;C07D491/22;C07D519/00 |
主分类号 |
A61K31/435 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|