摘要 |
A drug having a high affinity for benzodiazepine omega<SUB>3 </SUB>receptors and showing curative and preventive effects for anxiety and depression, which comprises as the active ingredient, for example, a compound of the formula (1): wherein R<SUP>1 </SUP>and R<SUP>2 </SUP>are independently a hydrogen atom, an optionally substituted alkyl group, an optionally substituted aryl group, etc., R<SUP>3 </SUP>and R<SUP>4 </SUP>are independently a hydrogen atom, an optionally substituted alkyl group, etc., R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7 </SUP>and R<SUP>8 </SUP>are independently a hydrogen atom, an optionally substituted alkyl group, an optionally substituted aryl group, etc., X is an oxygen atom, a sulfur atom, NR<SUP>10</SUP>, etc. (in which R<SUP>10 </SUP>is a hydrogen atom, an optionally substituted alkyl group, etc.)
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