ORALLY DISINTEGRABLE SLEEP AID FORMULATIONS

摘要

Orally dissolvable dosage forms comprising sleep aids such as benodiazepines are described. The dosage forms may be in the form of tablets or strips. In certain embodiments, the dosage forms may comprise particles, granules, microgranules, or crystals, and a matrix. The particles, granules or microgranules comprise a combination of immediate-release particles, granules or microgranules with sustained- release, delayed-release or enteric -coated particles, granules or microgranules. In one embodiment, the sleep aid is diazepam, triazolam, midazolam, temazepam, flurazepam, Zolpidem, zaleplon or a combination thereof. The sleep aids are typically employed in pharmaceutically effective amounts to treat insomnia.