| 摘要 |
An injectable Factor Xa inhibitor formulation is provided which includes the Factor Xa inhibitor razaxaban or apixaban, a solubilizing agent which is a substituted beta-cyclodextrin, preferably, sulfobutyl ether beta-cyclodextrin (SBE-CD) or hydroxypropyl-beta-cyclodextrin (HPB-CD), and water. A method for preventing or treating venous thrombosis, deep venous thrombosis and acute coronary syndrome employing the above formulation is also provided.
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