发明名称 2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF ß-SECRETASE (BACE)
摘要 The present invention is directed to 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of b-secretase, also known as b-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
申请公布号 WO2007092854(A2) 申请公布日期 2007.08.16
申请号 WO2007US61704 申请日期 2007.02.06
申请人 JANSSEN PHARMACEUTICA N.V.;BAXTER, ELLEN;REITZ, ALLEN B.;HUANG, YIFANG;CREIGHTON, CHRISTOPHER JOHN;MAHAROOF, UMAR SAIBU MOHOMED;REYNOLDS, CHARLES H.;LUO, CHI;TOUNGE, BRETT A.;ROSS, TINA MORGAN;LU, TIANBAO 发明人 BAXTER, ELLEN;REITZ, ALLEN B.;HUANG, YIFANG;CREIGHTON, CHRISTOPHER JOHN;MAHAROOF, UMAR SAIBU MOHOMED;REYNOLDS, CHARLES H.;LUO, CHI;TOUNGE, BRETT A.;ROSS, TINA MORGAN;LU, TIANBAO
分类号 主分类号
代理机构 代理人
主权项
地址