| 摘要 |
<p>[PROBLEMS] To provide a compound which has a novel structure and is effective against an influenza bacterium and an erythromycin-resistant bacterium (e.g., an erythromycin-resistant pneumococcal or streptococcal bacterium), as well as a conventional erythromycin-sensitive bacterium. [MEANS FOR SOLVING PROBLEMS] Disclosed is a novel 10a-azalide compound represented by the formula (I), a pharmaceutically acceptable salt or solvate thereof, or an intermediate for the production of the compound or the salt or solvate. The compound has an excellent bactericidal activity against an influenza bacterium, an erythromycin-resistant pneumococcal bacterium and the like, and therefore can be used as a therapeutic agent for an infectious disease.</p> |
| 申请人 |
TAISHO PHARMACEUTICAL CO., LTD.;MEIJI SEIKA KAISHA, LTD.;SUGIMOTO, TOMOHIRO;YAMAMOTO, KANAKO;MANAKA, AKIRA;OGITA, HARUHISA;KUROSAKA, JUN;KAWAMURA, MADOKA;KASHIMURA, MASATO;SASAMOTO, NAOKI;MIURA, TOMOAKI;KANEMOTO, KENICHI;OZAWA, TOMOHIRO;CHIKAUCHI, KEN;SHITARA, EIKI;KUBOTA, DAI |
发明人 |
SUGIMOTO, TOMOHIRO;YAMAMOTO, KANAKO;MANAKA, AKIRA;OGITA, HARUHISA;KUROSAKA, JUN;KAWAMURA, MADOKA;KASHIMURA, MASATO;SASAMOTO, NAOKI;MIURA, TOMOAKI;KANEMOTO, KENICHI;OZAWA, TOMOHIRO;CHIKAUCHI, KEN;SHITARA, EIKI;KUBOTA, DAI |
