COMBINATIONS COMPRISING A CDK INHIBITOR AND A GROWTH FACTOR ANTIBODY OR ANTI-MITOTIC

摘要

The present invention provides a combination comprising a compound A of formula (I) as set forth in the specification or a pharmaceutically acceptable salt thereof, and an antibody inhibiting a growth factor or its receptor and/or an antimitotic agent or a derivative or prodrug thereof, useful in the treatment of tumors. The chemical name of compound A is 8-[4-(4-methyl- piperazin-1-yl)- phenylamino]-1,4,4-trimethyl-4,5-dihydro-1H-pyrazolo[4,3- h]quinazoline-3-carboxylic acid methylamide.