NOVEL COUMARIN DERIVATIVE HAVING ANTITUMOR ACTIVITY

摘要

It is intended to provide a compound represented by the following general formula (1) or a pharmaceutically acceptable salt thereof. Because of having a sufficiently high antitumor activity, this compound or its salt is useful as a remedy for cell proliferative diseases, in particular, cancer. It is also intended to provide a medicinal composition which contains the above-described compound or its salt as the active ingredient. [Chemical formula 1] (1) wherein X is selected from heteroaryl, etc.; Y<SUP>1</SUP> and Y<SUP>2</SUP> are selected from -N=, etc.; Y<SUP>3</SUP> and Y<SUP>4</SUP> are selected from -CH=, etc.; A is selected from sulfamide, etc.; R<SUP>1</SUP> is selected from hydrogen, etc.; and R<SUP>2</SUP> is selected from C<SUB>1-6</SUB> alkyl, etc.