发明名称 Use of multimeric ligands of the TNF family with reduced toxicity for treating cell proliferative diseases
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a method for administering a ligand of a tumor necrosis factor (TNF) family having decreased toxicity for the purpose of treating disease in which cell growth should be controlled. <P>SOLUTION: A method for using the ligand of the TNF family of polymerized type for the purpose of preparing a medicament to be injected into a suitable body cavity selected from the abdominal cavity, thoracic cavity, pericardium, respiratory tract, upper alimentary canal, urinary passage, glenoid fossa, and central nervous system, wherein the ligand of the TNF family is selected from a Fas ligand, CD40L, TRAIL, and APRIL. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p>
申请公布号 EP1481687(B1) 申请公布日期 2007.08.15
申请号 EP20040356079 申请日期 2004.05.25
申请人 APOXIS SA 发明人 ROSAT, JEAN-PIERRE
分类号 A61K38/00;A61K38/19;A61K47/48;A61P1/00;A61P15/00;A61P35/00;A61P35/04 主分类号 A61K38/00
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