发明名称 |
New process for the manufacture of cephalosporin derivatives |
摘要 |
<p>The present invention is concerned with a novel process for the manufacture of cephalosporin derivatives of the general formula <CHEM> wherein R<1>, R<2> and R are defined in the specification, the process is characterized in that it comprises converting a phosphonium salt of the general formula <CHEM> wherein R is as above and Ph represents phenyl, into the corresponding ylide of the general formula <CHEM> wherein R and Ph are as above, and reacting same with an aldehyde of the general formula <CHEM> wherein R<1> and R<2> are as above.</p> |
申请公布号 |
EP1067131(B1) |
申请公布日期 |
2007.08.15 |
申请号 |
EP20000113739 |
申请日期 |
2000.06.29 |
申请人 |
BASILEA PHARMACEUTICA AG |
发明人 |
SPURR, PAUL;TRICKES, GEORG |
分类号 |
C07D501/38;C07D501/48;C07B61/00;C07D501/00;C07D501/04;C07D501/24;C07D501/46;C07D501/52;C07D501/56 |
主分类号 |
C07D501/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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