GENE CONSTRUCTION, VECTOR AND DNA VACCINE FOR THE VACCINATION OF AQUATIC ANIMALS

摘要

The gene construct comprises a nucleic acid sequence that encodes an immunogenic peptide of an aquatic animal pathogen under the control of an expression control sequence that can direct the expression of said immunogenic peptide in an aquatic animal and which comprises the sequence of a cytomegalovirus (CMV) promoter joined to an expression-enhancing sequence at position 5'. The vector comprises said gene construct and can be used to produce DNA vaccines that can be used to prevent infectious diseases in aquatic animals and is of particular interest in aquaculture. Said vaccines can be used for the mass vaccination of aquatic animals using an immersion/sonication process.