SUPERBRANCHED AMYLOPECTIN APPLICABLE IN METHODS FOR SURGICALLY AND THERAPEUTICALLY TREATING MAMMALS OR IN METHODS FOR DIAGNOSING DISEASES PRIMARILY AS VOLUME PLASMA-SUBSTITUTE

摘要

FIELD: medicine. ^ SUBSTANCE: method involves applying superbranched amylopectin or its derivative like hydroxyethylamylopectin possessing moderate branching degree expressed in anhydroglucose mole % of carrying bifurcation point being not greater than 10-25 mole % large and weighted average mass MM belonging to interval of 40000-800000 D. The amylopectin is applied in surgical and therapeutical methods for treating people or animals or in diagnostic purposes. The volume plasma-substitutes based on hydroxyethylated amylopectin have disadvantages occurred to present time as a result of hydroxyethylation application like incomplete metabolism and therefore accumulation in tissues with time that is related to adverse side effects. New plasma-substitutes based on polisaccharides are shown. ^ EFFECT: enhanced effectiveness of treatment; controlled dissociation under serum alpha-amylase. ^ 7 cl