摘要 |
Compounds of the following formula (I) wherein R<SUP>1 </SUP>R<SUP>2</SUP>, n, A<SUP>1 </SUP>and A<SUP>2 </SUP>are as defined in the specification, in vivo-hydrolysable precursors thereof, pharmaceutically acceptable salts thereof, the use in therapy and pharmaceutical compositions and methods of treatment using the same. The example compounds are 1-(2-(naphthylmethoxy)-1-phenylethyl)piperazine derivatives. The compounds are neurokinin 1 (NK<SUB>1</SUB>) receptor antagonist and/or serotonin reuptake inhibitors, with medical indications for depression and other disorders.
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