Novel purine derivatives, method for preparing them, their application as medicinal products, pharmaceutical compositions and novel use

摘要

The invention relates to novel products of formula (I): in which: Y represents N, O, S, CHR3 or -CR3 the dashed line representing a single or double bond, R and R1 represent in particular H, Hal, OH, alkyl, alkoxy, cyano, NO₂, NR4R5, trifluoromethyl, trifluoromethoxy, aryl, heteroaryl, -S(O)n-NR4R5 with n representing 0 to 2, acyl, -NH-CO-alkyl or -NH-CO-NH-phenyl, R3 represents H, Hal, alkyl, cyano, NO₂, NR4R5, trifluoromethyl or aryl, R2 represents R4, OR4, SR4 or NR4R5, R4 represents H, alkyl, cycloalkyl or aryl, either R4 and R5 are chosen from the values for R4, or R4 and R5 form, with N, a heterocyclic radical which may contain N, O and S, all these radicals being optionally substituted, these products being in all the isomeric forms and the salts, as medicinal products.