发明名称 |
Process for the preparation of imidazole compounds |
摘要 |
A process for the preparation of 4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone which comprises reacting 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone with a C6-8alkyllithium compound, 1-methylimidazole and a tri(C4-6alkyl)silyl halide to obtain better yields of the above product. |
申请公布号 |
AU2002253101(B2) |
申请公布日期 |
2007.08.09 |
申请号 |
AU20020253101 |
申请日期 |
2002.03.05 |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
RUDY LAURENT MARIA BROECKX;STEFAN MARCEL HERMAN LEURS;WALTER FERDINAND MARIA FILLIERS |
分类号 |
C07D401/06;A61K31/4709;A61P35/00;C07D403/06 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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