发明名称 VERFAHREN ZUR ENANTIOSELEKTIVEN SYNTHESE VON EINZELNEN MODAFINILENANTIOMEREN DURCH ASYMMETRISCHE OXIDATION
摘要 The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of : a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent ; and optionally b) isolating the obtained sulphoxide of formula (I). <CHEM> wherein n, Y, R1, R1a, R2 and R2a are as defined in claim 1.
申请公布号 DE602004007278(D1) 申请公布日期 2007.08.09
申请号 DE20046007278T 申请日期 2004.09.17
申请人 CEPHALON FRANCE 发明人 REBIERE, FRANCOIS;DURET, GERARD;PRAT, LAURENCE
分类号 C07C315/02;C07C317/44;C07C327/28 主分类号 C07C315/02
代理机构 代理人
主权项
地址