摘要 |
<p>Alloys of tricalcium phosphate and metal oxide such as TiO2 and SiO2 (ACP) are disclosed as well as method for making these alloys. Method for making these alloys include the steps of milling amorphous tricalcium phosphate and at least one metal oxide together in, for example, a ball mill operated under ambient conditions. Various aspects also relate to treating disease or damage to tissues such as enamel, dentine or bone by contacting tissue with these alloys. As well as formulations for oral care such as tooth pastes, mouth washes, tooth whiteners, and like that comprise ACP. Still another aspect is amorphous tricalcium phosphates that have antimicrobial activity. Various aspects disclosure methods for manufacturing these materials and for using them in various formulations and preparations such as dentifrices, mouth washes and rinses, teeth whiteners, gels, drenches, ointments, slaves, pastes, soaks, sprays, glues, cements, foodstuffs, and the like. Still another aspect is directed towards suing these compositions as parts of, or coatings for, devices such as needles, catheters, packagings, fillings, screws, pins, splints, implants, bandages, packings and the like.</p> |