| 发明名称 |
PEPTIDE HAVING REACTIVITY AS SUBSTRATE OF TRANSGLUTAMINASE AND UTILIZATION OF THE SAME |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a peptide having reactivity as a substrate of a transglutaminase. <P>SOLUTION: This peptide is provided by having the reactivity as the substrate of the transglutaminase consisting of a blood coagulation XIIIth factor and/or tissue type transglutaminase or having a specific amino acid sequence having transglutaminase inhibitor activity. The method for searching a compound having the transglutaminase inhibitory activity by utilizing the peptide presented by a phage-displaying method and a compound containing a primary amine is also provided. <P>COPYRIGHT: (C)2007,JPO&INPIT |
| 申请公布号 |
JP2007197434(A) |
申请公布日期 |
2007.08.09 |
| 申请号 |
JP20060352448 |
申请日期 |
2006.12.27 |
| 申请人 |
UNIV NAGOYA |
发明人 |
HITOMI KIYOTAKA;MAKI MASATOSHI;SUGIMURA TEISHO |
| 分类号 |
C07K7/08;A61K38/00;A61K38/55;A61L27/00;A61P1/04;A61P3/10;A61P7/02;A61P7/04;A61P9/10;A61P13/12;A61P17/00;A61P17/02;A61P17/10;A61P19/02;A61P25/00;A61P25/14;A61P25/28;A61P27/02;A61P27/12;A61P29/00;A61P31/04;A61P31/18;A61P33/02;A61P35/00;A61P35/04;A61P43/00;C12N9/10;C12N9/99;C12N15/09;C12P21/02;C12Q1/48 |
主分类号 |
C07K7/08 |
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