THERAPEUTIC AGENT FOR DRUG ABUSE AND ADDICTION COMPRISING SAIKOSAPONIN A AS ACTIVE INGREDIANT

摘要

A therapeutic agent for drug abuse and addiction comprising saikosaponin A as an active ingredient is provided to suppress drug dependency formed by administration of narcotic analgesics or narcotics and treat drug abuse and addiction safely. The therapeutic agent for drug abuse and addiction comprises saikosaponin A isolated from Bupleuri radix as an active ingredient and pharmaceutically acceptable carriers, wherein the saikosaponin A is isolated from the Bupleuri radix containing saikosaponin A, B, C and D, alpha-spinasterol, stigmasterol, bupleurmol and eugenol through hot water extraction and suppresses head twitch response in mouse induced by drug abuse and addiction.