Novel crystalline forms of an antagonist of CB1 cannabinoid receptor and preparation method thereof

摘要

The present invention relates to several crystalline forms and an amorphous form of an antagonist of CB 1 cannabinoid receptor and methods for their preparation. The present invention is also directed towards pharmaceutical compositions comprising these polymorphs ofrimonabant. The invention provides method of treating obesity, smoking cessation, overweight and related diseases by administering to a patient in need thereof a therapeutically effective amount of the different polymorphic forms and the amorphous form of the current invention.