Aerosol formulation for inhalation comprising a tiotropium salt

摘要

A medicament preparation (A) comprises: (1) a tiotropium salt as active agent (I) at a tiotropium concentration of 0.01-0.06 g/100 ml, (I) being in completely dissolved form; (2) water as sole solvent; (3) acid to adjust the pH to 2.7-3.1 (preferably 2.8-3.05); (4) a preservative; (5) a complexant and/or stabilizer; and optionally (6) other auxiliaries and additives. An independent claim is also included for the production of (A), by mixing the individual components. - ACTIVITY : Antiinflammatory; Antiasthmatic; Respiratory-Gen.. - MECHANISM OF ACTION : Anticholinergic.