Methods of treating and preventing Alzheimer's disease

摘要

The present invention relates to methods of treating or preventing the progression of Alzheimer's disease, by administering to a patient in need thereof certain thiosemicarbazone compounds. More particularly, the present invention relates to methods of preventing or treating neuronal damage and neuronal cell death occurring as a result of cellular insult of an amyloid-beta peptide. An example of such a thiosemicarbazone is 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811).