摘要 |
<p>The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.</p> |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, JEIL PHARM., CO., LTD., |
发明人 |
SUNG-EUN YOO;HYAE GYEONG CHEON;SUNG SOO KIM;SUNG-DON YANG;KWANG-ROK KIM;SANG DAL RHEE;JIN HEE AHN;SEUNG KYU KANG;WON HOON JUNG;SUNG DAE PARK;NAM GEE KIM;JAE MOK LEE;JONG HOON KIM;JEONG-HYUNG LEE;SEUNG JUN KIM;KIL WOONG MO;SUN MEE KIM;HYE JUNG KANG;KOUN HO LEE |